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CNG Channel antibody

Catalog Number:OM247610
OM247610
Discount Price
OM247610-100ul
1~2 Week
100ul
OM247610-50ul
50ul
1~2 Week
Product Profile
Product Name CNG Channel antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [CNC 9C1] to CNG ChannelThe protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Immunogen MBP-fusion protein of the C-terminal region of the a2 subunit (amino acids K581-D670)
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number CNC 9C1
Host Species Mouse
Tested Applications ICC/IFIHCWB
ICC/IF: 1:10 - 1:100:
Species Reactivity HumanMouseRat
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms cyclic nucleotide gated channel alpha 1
CNCG1
CNCG
RCNCalpha
RCNCa
CNG-1
RCNC1
RP49
CNGA1
CNG1
Target CNG Channel
Tissue Specificity This antibody is specific to the a2 subunit of the CNG channel.
Application

Application

Immunofluorescent analysis of CNG Channel in B-3 cells. CNG Channel staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with CNG Channel antibody [CNC 9C1] at a dilution of 1:20 over night at 4 ?C, washed with PBS and incubated with a proper secondary antibody. Images were taken at 60X magnification.
Application Notes ICC/IF: 1:10 - 1:100:
Additional Information
Form Liquid
Storage Instructions -20° C, Avoid Freeze/Thaw Cycles
Storage Buffer Ascites containing 0.05 % sodium azide
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