Application
Formalin-fixed paraffin-embedded colon carcinoma stained with COX2 antibody| Product Name | COX2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal to COX2 / Cyclooxygenase 2COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged. |
| Immunogen | Synthetic peptide (Rat) (C terminal). |
| Clonality | Monoclonal |
|---|---|
| Clone Number | SP21 |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC-P: 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | 29527, COX-2, Cox2, Ptgs2, COX 2 |
|---|---|
| Target | COX2 |
| Cellular Localization | Microsomal membrane |
Application
Formalin-fixed paraffin-embedded colon carcinoma stained with COX2 antibody| Application Notes | IHC-P: 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4 °C. |
| Storage Buffer | Preservative: 0.1% Sodium Azide Constituents: Tissue culture supernatant |
