Application
Immunofluorescence of CRISP in human testis tissue with CRISP antibody at 20 μg/mL.Application
Immunohistochemistry of CRISP2 in human testis tissue with CRISP2 antibody at 10 μg/mL.| Product Name | CRISP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CRISP2The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-P |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CT36 Cysteinerich secretory protein 2 GAPDL5 TPX1 TSP1 CRISP-2 CRISP2 Cysteine-rich secretory protein 2 Cysteinerich secretory protein2 CRISP 2 |
|---|---|
| Target | CRISP2 |
| Tissue Specificity | This antibody is specific for CRISP2 |
Application
Immunofluorescence of CRISP in human testis tissue with CRISP antibody at 20 μg/mL.
Application
Immunohistochemistry of CRISP2 in human testis tissue with CRISP2 antibody at 10 μg/mL.| Positive Control | Blocking Peptide: Cat.No. GTX85002-PEP - CRISP2 Peptide Lysates: Cat. No. GTX15374 - Human Testis Tissue Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
