| Product Name | CXCR4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal to CXCR4 / Fusin / LESTR / HUMSTRCXCR4, also termed Fusin, LESTR, or HUMSTR is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells. It is expressed predominantly on naive T-cells, subsets of peripheral blood, neutrophils, monocytes, and various cell lines. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 12G5 |
| Host Species | Mouse |
| Tested Applications | FACS |
| Blocks CD4-dependent infection by certain Ttropic strains of HIV-1. Blocks CD4-independent infection by HIV-2. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMonkeyBaboon |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | WHIM NPY3R NPYY3R FB22 LAP3 LCR1 162643 NPYR 7852 HM89 HSY3RR P61073 NPYRL CD184 D2S201E LESTR CXCR4 |
|---|---|
| Target | CXCR4 |
| Cellular Localization | Cell Membrane |
| Positive Control | HeLa Cells |
|---|---|
| Application Notes | Blocks CD4-dependent infection by certain Ttropic strains of HIV-1. Blocks CD4-independent infection by HIV-2. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4, containing 0.2% BSA and 0.1% sodium azide |
