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CYP1A1 antibody

Catalog Number:OM248889
OM248889
Discount Price
OM248889-100ul
1~2 Week
100ul
OM248889-50ul
50ul
1~2 Week
Product Profile
Product Name CYP1A1 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [6G5] to CYP1A1This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to a region within amino acids 203 and 461 of human CYP1A1.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 6G5
Host Species Mouse
Tested Applications ELISAIHC-PWB
Recommended Starting Dilutions: ELISA: 1/10000. WB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. Not yet tested in other applications. Determining optimal working dilutions by titration test.:
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms P1-450
CYP1
AHRR
AHH
P450-C
CP11
P450DX
Target CYP1A1
Molecular Weight(MW) 58 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using CYP1A1 antibody [6G5].

Application

WB analysis of human CYP1A1 (a.a. 203-461) recombinant protein using CYP1A1 antibody [6G5].

Application

IHC-P analysis of rectum cancer tissues using CYP1A1 antibody [6G5].

Application

IHC-P analysis of ovarian cancer tissues using CYP1A1 antibody [6G5].
Application Notes Recommended Starting Dilutions: ELISA: 1/10000. WB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. Not yet tested in other applications. Determining optimal working dilutions by titration test.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
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