| Product Name | Cytokeratin 13 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [AE8] to Cytokeratin 13Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. This antibody is specific for Cytokeratin 13, which is a marker for oesophageal type differentiation which is expressed by various internal stratified epithelia. |
| Immunogen | Rabbit esophageal keratins |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | AE8 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| For WB: Use at 1:1000-1:3000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | 148065 Cytokeratin 13 P13646 3860 KRT13 Cytokeratin13 CK13 K13 MGC3781 |
|---|---|
| Target | Cytokeratin 13 |
| Tissue Specificity | Human Keratin K13 (~51K) |
| Application Notes | For WB: Use at 1:1000-1:3000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS + 0.1% sodium azide |
