Rabbit Polyclonal antibody to DCLRE1BDNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DCLRE1B. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
APOLLO SNMIB SNM1B DNA cross-link repair 1B
Target
DCLRE1B
Tissue Specificity
Recognizes endogenous levels of DCLRE1B protein.
Application
Application
Western blot analysis of DCLRE1B expression in HOS (A) whole cell lysates.
WB
RT-qPCR (A, B) and western blot (C, D) were used to measure DCLRE1B and HOMER1 expressions.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.