Rabbit polyclonal to DcR1First named mouse TNFRH1 (tumor necrosis factor receptor homologue 1), mouse DcTRAILR1 (decoy TRAIL receptor 1) this protein has been confirmed to be a receptor for TRAIL using ligand-receptor binding assays. However, overexpression was not found to cause NF-kB activation or apoptosis, as would be expected of a TRAIL receptor. These observations lead researchers to rename the protein DcTRAILR1, or decoy TRAIL receptor 1.
Immunogen
Synthetic peptide corresponding to amino acids 155-168 (CSSSVSNPRNWLFL) of mouse DcR1; GenBank no: NP_077252.2.?
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a concentration of 1 - 3 μg/ml. Detects a band of approximately 23 kDa. The 23 kD band may represent the long form of this protein (predicted molecular weight: 20 kDa). Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Mouse
Concentration
0.5mg/ml
Purification
Protein G
Target Information
Gene Synonyms
DCR1 8794 TRID DcTRAILR1 603613 TNFRSF10C LIT TRAILR3 O14798
Target
DcR1
Cellular Localization
Attached to the membrane by a GPI-anchor.
Application
Application
Western blot analysis of DcTrailR in 15 ugs of mouse spleen cell lysate at 1 ug/ml.
Positive Control
mouse spleen whole cell lysate.
Application Notes
WB: Use at a concentration of 1 - 3 μg/ml. Detects a band of approximately 23 kDa. The 23 kD band may represent the long form of this protein (predicted molecular weight: 20 kDa). Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.