Mouse monoclonal antibody [BD6] to Dectin-1This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
BD6
Host Species
Mouse
Tested Applications
FACS
Flow Cytometry: 1/25 - 1/200 Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BGR , CANDF4 , DECTIN1 , CLEC7A , CLECSF12 , C-type lectin domain family 7, member A
Target
Dectin-1
Tissue Specificity
This antibody recognizes Dectin-1.
Application
Application
FACS ImageStaining of human peripheral blood monocytes with Mouse anti Human Dectin-1:FITC
Application
FACS ImageStaining of human peripheral blood granulocytes with Mouse anti Human Dectin-1:RPE
Application Notes
Flow Cytometry: 1/25 - 1/200 Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.