Application
FACS analysis of human peripheral blood monocytes using Dectin-1 antibody [GE2] (Low endotoxin, azide free).| Product Name | Dectin-1 antibody [GE2] (Azide free) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [GE2] to Dectin-1This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | GE2 |
| Host Species | Mouse |
| Tested Applications | FACSFunctional Assay |
| Flow Cytometry: Neat - 1/25 Optimal dilution / concentration should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BGR , CANDF4 , DECTIN1 , CLEC7A , CLECSF12 , C-type lectin domain family 7, member A |
|---|---|
| Target | Dectin-1 |
| Tissue Specificity | This antibody recognizes both of these isoforms. Clone GE2 could be used to inhibit receptor function. |
Application
FACS analysis of human peripheral blood monocytes using Dectin-1 antibody [GE2] (Low endotoxin, azide free).| Application Notes | Flow Cytometry: Neat - 1/25 Optimal dilution / concentration should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
