| Product Name | Defensin alpha 1 antibody [DEF3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [DEF-3] to Defensin alpha 1Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, May 2010] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | DEF-3 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-PWB |
| Immunohistology - Frozen: 0.1 - 0.5 ug/ml | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MRS , HNP-1 , HP1 , DEF1 , DEFA1 , DEFA2 , HP-1 |
|---|---|
| Target | Defensin |
| Tissue Specificity | This antibody recognizes defensins alpha 1-3. |
| Application Notes | Immunohistology - Frozen: 0.1 - 0.5 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Prior to reconstitution store at +4°C. After reconstitution store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) 0.5% Bovine Serum Albumin |
