| Product Name | Desmoglein 2 antibody [3G132] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [3G132] to Desmoglein 2Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. |
| Immunogen | Full length native protein (purified) (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3G132 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIPWB |
| For IF: Use at a concentration of 20-50 μg/ml. For IP: Use at a concentration of 5-10 μg/ml (native). For WB: Use at a concentration of 1-3 μg/ml. Not tested in other applicaions. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Protein A |
| Gene Synonyms | HDGC, MGC117034, CDHF5, 125671, MGC117036, MGC117037, 1829, DSG2, Q14126, Desmoglein2, Desmoglein 2 |
|---|---|
| Target | Desmoglein 2 |
| Tissue Specificity | This antibody does not cross-react with Desmoglein 1 or Desmoglein 3. |
| Cellular Localization | Cell Membrane |
| Positive Control | A431 cells |
|---|---|
| Application Notes | For IF: Use at a concentration of 20-50 μg/ml. For IP: Use at a concentration of 5-10 μg/ml (native). For WB: Use at a concentration of 1-3 μg/ml. Not tested in other applicaions. Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage add 50% glycerol, aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide |
