| Product Name | Desmoglein 2 antibody [6D8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [6D8] to Desmoglein 2Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. |
| Immunogen | Unfortunately, this information is considered to be commercially sensitive |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6D8 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIPWB |
| IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | Desmoglein2 |
|---|---|
| Target | Desmoglein 2 |
| Tissue Specificity | reacts with Desmoglein 2. Does not cross-react with Desmoglein 1 or Desmoglein 3. |
| Cellular Localization | Cell Membrane |
| Positive Control | Colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. |
|---|---|
| Application Notes | IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: 0.1% BSA, PBS |
