| Product description |
Mouse monoclonal [1.BB.891] to DihydrostreptomycinThe first aminoglycoside was streptomycin, which was created from the fungus like bacterium Streptomyces griseus. Streptomycin's ototoxic potential was recognized quite early. In response, researchers modified the drug's molecule and created dihydrostreptomycin. Unlike its predecessor, dihydrostreptomycin is much more cochleotoxic than it is vestibulotoxic; in fact, it is almost exactly as cochleotoxic as streptomycin is vestibulotoxic. Later, investigators tried to reduce the risk of both toxicities by combining equal amounts of the two drugs, but this only resulted in patients experiencing both toxicities rather than neither. |