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DNA polymerase gamma antibody , N-term

Catalog Number:OM250248
OM250248
Discount Price
OM250248-100ul
1~2 Week
100ul
OM250248-50ul
50ul
OM250248-20ul
20ul
1~2 Week
Product Profile
Product Name DNA polymerase gamma antibody , N-term
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human DNA polymerase gamma. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanRat
Predicted Reactivity MouseMouse (82%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms FLJ27114 antibody
MDP1 antibody
MIRAS antibody
MTDPS4A antibody
MTDPS4B antibody
PEO antibody
POLG1 antibody
POLGA antibody
SANDO antibody
SCAE antibody
POLG antibody
PolG
catalytic subunit antibody
DNA polymerase subunit gamma-1 antibody
mit
Molecular Weight(MW) 140 kDa (note) (3)
Cellular Localization Mitochondrion
Application

Application

Immunohistochemical analysis of paraffin-embedded U87 xenograft, using DNA polymerase gamma antibody at 1:500 dilution.

Application

DNA polymerase gamma antibody [N1N2], N-term detects POLG protein by Western blot analysis. A. 50 µg rat testis lysate/extract 5 % SDS-PAGE DNA polymerase gamma antibody [N1N2], N-term dilution: 1:500

Application

Sample (30 ug of whole cell lysate) A: NT2D1 5% SDS PAGE diluted at 1:1000
Positive Control NT2D1 , rat testis
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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