Mouse Monoclonal antibody [2A1] to EMR2This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Immunogen
NIH-3T3 cells stably transfected with EMR2 (EGF1-5) cDNA
FACS analysis of human peripheral blood granulocytes using EMR2 antibody [2A1].
Application Notes
FACS: 1:50 – 1:200. IHC-Fr: 1:50 – 1:200
Additional Information
Form
Liquid
Storage Instructions
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.