Application
Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 10% SDS-PAGE Endothelin B Receptor antibody [C3], C-term dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Application
Immunohistochemical analysis of paraffin-embedded human gingiva, using Endothelin B receptor antibody at 1:100 dilution.Application
Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis. A. 30 µg A375 whole cell lysate/extract 10% SDS-PAGE Endothelin B Receptor antibody [C3], C-term dilution: 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Product Name | Endothelin B Receptor antibody [C3], C-term |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Endothelin B Receptor (endothelin receptor type B)The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Endothelin B Receptor. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanRat |
| Predicted Reactivity | Mouse, Dog, Pig, Rabbit, Chicken, BovineMouse (100%), Dog (100%), Pig (100%), Rabbit (100%), Chicken (100%), Bovine (100%) |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ABCDS antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, EDNRB antibody, endothelin receptor non-selective type antibody, endothelin B receptor antibody, endothelin receptor type B antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa (note) (3) |
| Cellular Localization | Cell membrane |
Application
Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 10% SDS-PAGE Endothelin B Receptor antibody [C3], C-term dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Application
Immunohistochemical analysis of paraffin-embedded human gingiva, using Endothelin B receptor antibody at 1:100 dilution.
Application
Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis. A. 30 µg A375 whole cell lysate/extract 10% SDS-PAGE Endothelin B Receptor antibody [C3], C-term dilution: 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
