Application
Sample (30 ug of whole cell lysate) A: A431 B: H1299 10% SDS PAGE diluted at 1:1000Application
ETBR antibody [N1N2], N-term detects ETBR protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: ETBR antibody [N1N2], N-term dilution: 1:250.| Product Name | Endothelin B Receptor antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ETBR (endothelin receptor type B)The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human ETBR. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ABCDS antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, EDNRB antibody, endothelin receptor non-selective type antibody, endothelin B receptor antibody, endothelin receptor type B antibody |
|---|---|
| Target | ETBR |
| Molecular Weight(MW) | 50 kDa (note) (4) |
| Cellular Localization | Cell membrane |
Application
Sample (30 ug of whole cell lysate) A: A431 B: H1299 10% SDS PAGE diluted at 1:1000
Application
ETBR antibody [N1N2], N-term detects ETBR protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: ETBR antibody [N1N2], N-term dilution: 1:250.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 50% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
