Application
Western blot analysis using ETV1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV1 cDNA (2).Application
Western blot analysis using anti-ETV1 monoclonal antibody against truncated Trx-ETV1 recombinant protein(1) and full-length ETV1(aa1-477)-hIgGFc transfected CHO-K1 cell lysate(2).| Product Name | ER81 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1C8B6] to ER81This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [ |
| Immunogen | The immunogen corresponding to a region within amino acids 1 and 191 of ER81 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1C8B6 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ER81 |
|---|---|
| Target | ETV1 |
Application
Western blot analysis using ETV1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV1 cDNA (2).
Application
Western blot analysis using anti-ETV1 monoclonal antibody against truncated Trx-ETV1 recombinant protein(1) and full-length ETV1(aa1-477)-hIgGFc transfected CHO-K1 cell lysate(2).| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
