Application
IHC-P analysis of human breast cancer tissue using Estrogen Receptor beta 5 antibody [5/25].| Product Name | Estrogen Receptor beta 5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [5/25] to Estrogen Receptor beta 5This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | Tuberculin conjugated synthetic peptide LLSHVRHARYAP derived from the C-terminus of human Estrogen Receptor beta 5 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5/25 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ESR-BETA ERB ESR2 ESTRB ESRB ER-BETA NR3A2 |
|---|---|
| Target | Estrogen Receptor Beta 5 |
| Tissue Specificity | This antibody recognizes human estrogen receptor beta 5 (ERB5). |
Application
IHC-P analysis of human breast cancer tissue using Estrogen Receptor beta 5 antibody [5/25].| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.1% Sodium Azide (NaN3) |
