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FBXW11 antibody

Catalog Number:OM252785
OM252785
Discount Price
OM252785-100ul
1~2 Week
100ul
OM252785-50ul
50ul
OM252785-20ul
20ul
1~2 Week
Product Profile
Product Name FBXW11 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to FBXW11 (F-box and WD repeat domain containing 11)This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human FBXW11. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouse
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms BTRC2 antibody
BTRCP2 antibody
FBW1B antibody
FBXW1B antibody
Fbw11 antibody
Hos antibody
KIAA0696 antibody
FBXW11 antibody
F-box and WD-40 domain protein 1B antibody
F-box and WD repeats protein beta-TrCP2 antibody
F-box protein Fbw1b antibody
Molecular Weight(MW) 62 kDa (note) (4)
Application

Application

Sample (30 µg of whole cell lysate) A: HeLa B: HepG2 7.5% SDS PAGE diluted at 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Application

FBXW11 antibody detects FBXW11 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: FBXW11 protein stained by FBXW11 antibody diluted at 1:500. Blue: Hoechst 33343 staining.

Application

Sample (30 µg of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7.5% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Application

FBXW11 antibody detects FBXW11 protein at cytoplasm in human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. FBXW11 antibody diluted at 1:500.
Positive Control HeLa , HepG2 , NIH-3T3 , JC , BCL-1
Application Notes *Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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