Rabbit polyclonal antibody to FBXW11 (F-box and WD repeat domain containing 11)This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human FBXW11. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BTRC2 antibody BTRCP2 antibody FBW1B antibody FBXW1B antibody Fbw11 antibody Hos antibody KIAA0696 antibody FBXW11 antibody F-box and WD-40 domain protein 1B antibody F-box and WD repeats protein beta-TrCP2 antibody F-box protein Fbw1b antibody
Molecular Weight(MW)
62 kDa (note) (3)
Application
Application
Sample(30 μg of whole cell lysate) A:293T B:A431 C:H1299 7.5% SDS PAGE diluted at 1:500
Positive Control
293T , A431 , H1299 , HeLaS3
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.