Application
Western blot analysis using anti-FGFR1 monoclonal antibody against extracellular domain of human FGFR1 (aa33-376).| Product Name | FGFR1 antibody [3D4F7] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3D4F7] to FGFR1The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosoma |
| Immunogen | The immunogen corresponding to a region within amino acids 33 and 423 of human FGFR1 fused with hIgGFc tag expressed in HEK293 cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 3D4F7 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BFGFR , BFGF-R-1 , FLT-2 , FLG , CD331 , FLT2 , FGFBR , HH2 , OGD , CEK , FGFR-1 , KAL2 , N-SAM , HBGFR |
|---|---|
| Target | FGFR1 |
| Molecular Weight(MW) | 92 kDa (note) |
Application
Western blot analysis using anti-FGFR1 monoclonal antibody against extracellular domain of human FGFR1 (aa33-376).| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
