Application
Immunohistochemical analysis of paraffin-embedded human liver tissues using anti-FGFR4 mAb.Application
Western blot analysis using FGFR4 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY FGFR4 cDNA (2).Application
Western blot analysis using anti-FGFR4 monoclonal antibody against truncated FGFR4 recombinant protein(1).| Product Name | FGFR4 antibody [4H2B10B2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4H2B10B2] to FGFR4The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This partic |
| Immunogen | The immunogen corresponding to FGFR4 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4H2B10B2 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD334 , TKF , JTK2 |
|---|---|
| Target | FGFR4 |
| Molecular Weight(MW) | 88 kDa (note) |
| Cellular Localization | Isoform 2 may be secreted. |
Application
Immunohistochemical analysis of paraffin-embedded human liver tissues using anti-FGFR4 mAb.
Application
Western blot analysis using FGFR4 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY FGFR4 cDNA (2).
Application
Western blot analysis using anti-FGFR4 monoclonal antibody against truncated FGFR4 recombinant protein(1).| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
