Application
Western blot analysis using anti-Fibulin5 monoclonal antiobdy against truncated fibulin5 recombinant protein(1) and Hela cell lysate(2).Application
Immunohistochemical analysis of paraffin-embedded human stomach carcinoma(left) and breast carcinoma(right), showing cytoplasmic localization using fibulin5 antibody with DAB staining.| Product Name | Fibulin 5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3F10A5, 3F8A12] to Fibulin 5The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to Fibulin 5 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3F10A5, 3F8A12 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DANCE ARMD3 UP50 FBLN5 ADCL2 ARCL1A FIBL-5 EVEC |
|---|---|
| Target | Fibulin 5 |
Application
Western blot analysis using anti-Fibulin5 monoclonal antiobdy against truncated fibulin5 recombinant protein(1) and Hela cell lysate(2).
Application
Immunohistochemical analysis of paraffin-embedded human stomach carcinoma(left) and breast carcinoma(right), showing cytoplasmic localization using fibulin5 antibody with DAB staining.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
