Mouse monoclonal antibody [3F8D5,7F8D5] to Fibulin 5The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to Fibulin 5 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgM
Clone Number
3F8D5,7F8D5
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
EVEC FIBL-5 ARCL1A ADCL2 FBLN5 UP50 ARMD3 DANCE
Target
Fibulin 5
Application
Application
Western blot analysis using anti-fibulin5 monoclonal antiobdy against truncated fibulin5 recombinant protein(1) and Hela cell lysate(2).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.