Application
Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE diluted at 1:1000| Product Name | Filamin A antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Filamin A (filamin A, alpha)The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Filamin A. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rabbit, BovineMouse (98%), Rat (96%), Rabbit (98%), Bovine (98%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ABP-280 antibody ABPX antibody CVD1 antibody DKFZp434P031 antibody FLN antibody FLN-A antibody FLN1 antibody FMD antibody MNS antibody NHBP antibody OPD antibody OPD1 antibody OPD2 antibody XLVD antibody XMVD antibody FLNA antibody filamin- |
|---|---|
| Molecular Weight(MW) | 281 kDa (note) (2) |
| Cellular Localization | Cytoplasm , cell cortex , cytoskeleton |
Application
Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
