Mouse monoclonal [1.BB.804] to FilaminFilamin functions as a crosslinking protein forming a flexible link between two actin filaments. It is composed of two identical polypeptide chains each joined to the other at one end, with an actin binding site at the other. It is present in human platelets, lymphocytes, fibroblasts and smooth muscle actin.
Immunogen
Filamin (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1.BB.804
Host Species
Mouse
Tested Applications
IHC-FIHC-PWB
IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 250 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanPigRatGuinea Pig
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Synonyms
FRA1B 2361 Filamin
Target
Filamin
Cellular Localization
Cytoplasmic. A small amount localizes at membranes. In striated muscle cells, it predominantly localizes in myofibrillar Z-disks, while a minor fraction localizes with subsarcolemme.
Application Notes
IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 250 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.