Mouse monoclonal [FIL - 7B10] to FilensinMore than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF).
Immunogen
Human and bovine lens filament enriched fraction (plasma membrane cytoskeleton complex).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
FIL-7B10
Host Species
Mouse
Tested Applications
ICC/IFWB
IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 115 kDa (full length filensin) and a band of approximately 53 kDa (processed filensin fragment). It also reacts with a variety of breakdown products of filensin in the range of 28-69 kDa. Optimal dilutions/concentrations should be determined by the end user.:
IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 115 kDa (full length filensin) and a band of approximately 53 kDa (processed filensin fragment). It also reacts with a variety of breakdown products of filensin in the range of 28-69 kDa. Optimal dilutions/concentrations should be determined by the end user.: