Application
WB analysis of human FLT3 recombinant protein using FLT3 antibody [7B7C3].Application
IHC-P analysis of liver cancer tissues using FLT3 antibody [7B7C3].Application
IHC-P analysis of cervical cancer tissues using FLT3 antibody [7B7C3].Application
ELISA analysis of control antigen and antigen using FLT3 antibody [7B7C3].| Product Name | FLT3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal Antibody [7B7C3] to FLT3This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to a region within amino acids 930 and 991 of human FLT3 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7B7C3 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | FLK-2 STK1 CD135 FLK2 |
|---|---|
| Target | FLT3 |
| Molecular Weight(MW) | 130 kDa (note) |
Application
WB analysis of human FLT3 recombinant protein using FLT3 antibody [7B7C3].
Application
IHC-P analysis of liver cancer tissues using FLT3 antibody [7B7C3].
Application
IHC-P analysis of cervical cancer tissues using FLT3 antibody [7B7C3].
Application
ELISA analysis of control antigen and antigen using FLT3 antibody [7B7C3].| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
