Rabbit Polyclonal antibody to Fos B (FBJ murine osteosarcoma viral oncogene homolog B)The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Fos B. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
HumanMouse
Predicted Reactivity
Rat, Dog, BovineRat (87%), Dog (96%), Bovine (98%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
AP-1 antibody DKFZp686C0818 antibody G0S3 antibody GOS3 antibody GOSB antibody MGC42291 antibody FOSB antibody G0/G1 switch regulatory protein 3 antibody protein fosB antibody activator protein 1 antibody FBJ murine osteosarcoma viral oncogene ho
Molecular Weight(MW)
36 kDa (note)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: NIH-3T3 10% SDS PAGE diluted at 1:1000
Application
Fos B antibody detects FOSB protein by Western blot analysis. A. 30 µg HeLa whole cell lysate/extract 15 % SDS-PAGE Fos B antibody dilution: 1:1000
Positive Control
HeLa , NIH-3T3
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.