Rabbit polyclonal antibody to FoxH1FoxH1 (also known as Forkhead box H1 or FAST-1) is a transcription factor that shares close homology with Xenopus FAST-1. FoxH1 binds to SMAD2/4 and activates activin response through a DNA binding motif region that consist of TGT(G/T)(T/G)ATT sequence. FoxH1 binding to Smad2/Smad4/FAST1 forms a transcriptionally complex structure that can induced TGFbeta signal transduction.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~44kDa of FoxH1 from samples of human, mouse and rat origins. Reactivity to other species has not been tested.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Forkhead activin signal transducer1 FAST1 Forkhead activin Signal Transducer2 FOXH 1 FOXH1 Forkhead activin Signal Transducer 2 Forkhead box protein H1 Forkhead activin signal transducer 1 FOX H1 FAST-1 Forkhead box H1 FAST 1
Target
FoxH1
Tissue Specificity
This antibody is specific for FoxH1.
Application
Application
Western blot analysis of FoxH1 expression in 3T3 cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~44kDa of FoxH1 from samples of human, mouse and rat origins. Reactivity to other species has not been tested.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.