Application
Immunofluorescence of FREM2 in A20 cells with FREM2 antibody at 20 ug/mL.| Product Name | FREM2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to FREM2FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IF |
| ICC/IF:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FRAS1related extracellular matrix protein 2 FREM2 FRAS1related extracellular matrix protein2 FRAS1-related extracellular matrix protein 2 |
|---|---|
| Target | FREM2 |
| Tissue Specificity | This antibody is specific for FREM2 |
Application
Immunofluorescence of FREM2 in A20 cells with FREM2 antibody at 20 ug/mL.| Positive Control | Blocking Peptide: Cat.No. GTX85004-PEP - FREM2 Peptide Lysates: Cat. No. GTX27180 - A-20 Cell Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
