Mouse monoclonal [1G2] to FXR2Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
Immunogen
Recombinant C-terminal fragment of human FXR2 (residues 414-658)
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1G2
Host Species
Mouse
Tested Applications
WB
For WB: Use at a dilution of 1:500 - 1:2,500. A band is seen at ~80 kDa. Theoretical MW is 74 kDa. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FMR1L2 FXR2P
Target
FXR2
Tissue Specificity
This antibody is specific for FXR2 protein
Light Chain Type
kappa
Application
Application
Western Blot: FXR2 Antibody (1G2) [ - Whole cell HeLa lysate at a concentration of 1:2500 (lane 1) and 1:500 (lane 2).
Positive Control
HeLa whole cell lysate
Application Notes
For WB: Use at a dilution of 1:500 - 1:2,500. A band is seen at ~80 kDa. Theoretical MW is 74 kDa. Optimal dilutions/concentrations should be determined by the researcher.:
Additional Information
Form
Liquid
Storage Instructions
Store this antibody at 4 dgrees Celcius for short-term storage. For long-term storage, aliquot into working amounts and store at -20 degrees Celcius. Avoid freeze-thaw cycles.