Application
Sample(30 μg of whole cell lysate) A:A431 12% SDS PAGE diluted at 1:500Application
Galanin Receptor 2 antibody detects Galanin Receptor 2 protein at membrane and cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. Galanin Receptor 2 antibody dilution: 1:500.Application
Galanin Receptor 2 antibody detects GALR2 protein at membrane on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. Galanin Receptor 2 antibody dilution: 1:500.| Product Name | Galanin Receptor 2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Galanin Receptor 2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanRat |
| Predicted Reactivity | Bovine, Chicken, MouseMouse (92%), Chicken (86%), Bovine (93%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | GALNR2 antibody MGC125983 antibody MGC125984 antibody GALR2 antibody GALR-2 antibody GAL2-R antibody galanin receptor type 2 antibody galanin receptor 2 antibody |
|---|---|
| Molecular Weight(MW) | 42 kDa (note) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
Application
Sample(30 μg of whole cell lysate) A:A431 12% SDS PAGE diluted at 1:500
Application
Galanin Receptor 2 antibody detects Galanin Receptor 2 protein at membrane and cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. Galanin Receptor 2 antibody dilution: 1:500.
Application
Galanin Receptor 2 antibody detects GALR2 protein at membrane on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. Galanin Receptor 2 antibody dilution: 1:500.| Positive Control | A431 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 50% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
