Application
ELISA analysis of control antigen and antigen using GCK antibody [4G6].Application
WB analysis of human GCK (a.a. 1-198) recombinant protein using GCK antibody [4G6].Application
WB analysis of lysates from (1) untransfected and (2) GCK-hIgGFc transfected HEK293 cells using GCK antibody [4G6].| Product Name | GCK antibody [4G6] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal Antibody [4G6] to GCKHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009] |
| Immunogen | The immunogen corresponding to human GCK expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4G6 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GLK , HHF3 , LGLK , HXKP , GK , FGQTL3 , HKIV , MODY2 , HK4 |
|---|---|
| Target | GCK |
| Molecular Weight(MW) | 52 kDa (note) |
Application
ELISA analysis of control antigen and antigen using GCK antibody [4G6].
Application
WB analysis of human GCK (a.a. 1-198) recombinant protein using GCK antibody [4G6].
Application
WB analysis of lysates from (1) untransfected and (2) GCK-hIgGFc transfected HEK293 cells using GCK antibody [4G6].| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
