| Product Name | GNAI1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [SPM397] to G protein alpha inhibitor 1GTP binding proteins (G proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G proteins. Gi consists of three different subtypes of alpha subunits (alpha i1, alpha i2 and alpha i3). |
| Immunogen | Partially purified rat brain G alpha i1 protein. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | SPM397 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB: Use at an assay dependent dilution. Predicted molecular weight: 40 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMousePigRatGuinea PigBovine |
| Concentration | 0.2mg/ml |
| Purification | Protein A |
| Gene Synonyms | P63096 Gi GNAI1 2770 139310 25686 BPGTPB |
|---|---|
| Target | GNAI1 |
| Tissue Specificity | Highly specific to G alpha i1 and shows no cross reaction with transducin, G alpha 0, G alpha i2, G alpha i3, or G alpha s. ADP ribosylation of alpha i1 protein does not alter the reactivity of the antibody. |
| Cellular Localization | Cell Membrane |
| Positive Control | IMR5 cells. Brain |
|---|---|
| Application Notes | WB: Use at an assay dependent dilution. Predicted molecular weight: 40 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4ºC |
| Storage Buffer | Preservative: Sodium Azide. Constituents: 0.2% BSA, 10mM PBS. pH 7.4 |
