Application
Western blot analysis of HCN1 in rat brain membrane lysates using a 1:1000 dilution ofApplication
IHC analysis of HCN1 using tested on mouse cerebellum. Strong cytoplasm staining of the cerebellum giant neurons.Application
IHC analysis of HCN1 in frozen sections of mouse brain extract using| Product Name | HCN1 antibody [S70-28] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [S70-28] to HCN1Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP, and at 10-100 times higher concentrations, also by cGMP (By similarity). May mediate responses to sour stimuli. |
| Immunogen | Fusion protein amino acids 778-910 (C terminus) of rat HCN1, accession number Q9JKBO |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | S70-28 |
| Host Species | Mouse |
| Tested Applications | IHCIHC-FIPWB |
| We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF). | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | potassium/sodium hyperpolarization activted cycli nucleotide gated channel1, BCNG1, HAC2, potassium/sodium hyperpolarization activted cycli nucleotide gated channel 1 |
|---|---|
| Target | HCN1 |
| Molecular Weight(MW) | 100kDa (note) |
| Tissue Specificity | No cross-reactivity against HCN2 |
Application
Western blot analysis of HCN1 in rat brain membrane lysates using a 1:1000 dilution of
Application
IHC analysis of HCN1 using tested on mouse cerebellum. Strong cytoplasm staining of the cerebellum giant neurons.
Application
IHC analysis of HCN1 in frozen sections of mouse brain extract using| Application Notes | We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF). |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
