Application
Western blot analysis using anti-HDAC3 monoclonal antibody against truncated Trx-HDAC3 recombinant protein(1), full length HDAC3-hIgGFc (aa1-428) transfected CHO-K1 cell lysate(2) and Hela cell lysate(3).Application
Immunohistochemical analysis of paraffin-embedded human esophagus cancer(left) and breast carcinoma tissue(right), showing nuclear localization with DAB staining using anti-HDAC3 Antibody.| Product Name | HDAC3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3A7B5] to HDAC3Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to a region within amino acids 224 and 428 of HDAC3 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3A7B5 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RPD3 HD3 RPD3-2 |
|---|---|
| Target | HDAC3 |
| Molecular Weight(MW) | 48.8 kDa (note) |
Application
Western blot analysis using anti-HDAC3 monoclonal antibody against truncated Trx-HDAC3 recombinant protein(1), full length HDAC3-hIgGFc (aa1-428) transfected CHO-K1 cell lysate(2) and Hela cell lysate(3).
Application
Immunohistochemical analysis of paraffin-embedded human esophagus cancer(left) and breast carcinoma tissue(right), showing nuclear localization with DAB staining using anti-HDAC3 Antibody.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
