Rabbit Polyclonal antibody to Heat Shock Protein 104Heat shock proteins (HSP) are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs including HSP70, HSP90 and HSP100. The HSP100 proteins generally have amino acid sequences of about 900 residues and contain two nucleotide-binding sites. Within the HSP100 family of proteins, yeast express a ~104 kDa form which is necessary to protect cells from various stress conditions such as heat, heavy metals and ethanol, though mutation studies have shown that the protein is not required for normal growth. Yeast HSP104 has been shown to be a ClpB protein with significant sequence homology to E. coli ClpB, particularly in the two nucleotide-binding sites.
Immunogen
Synthetic peptide corresponding to the C-terminal residues D(894) D D N E D S M E I D D D L D(908) of S. cerevisiae HSP104.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
WB: 1 ug/ml Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Yeast
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HSP104
Target
Heat Shock Protein 104
Application
Application
WB analysis using Heat Shock Protein 104 antibody.
Application Notes
WB: 1 ug/ml Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
PBS containing 1 mg/ml BSA and 0.05% sodium azide.