| Product Name | Hepatitis B surface antigen antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [HB11] to Hepatitis B Virus Surface AntigenHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. |
| Immunogen | Recombinant full length protein (HBsAg of ayw subtype) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | HB11 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. This antibody is recommended for use in an ELISA pair with GTX22039. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Hepatitis B virus |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | HBsAg antibody Hep B surface antigen antibody Hepatitis B surface antigen antibody Hepatitis B Virus major surface antigen antibody Hepatitis B virus S antigen antibody |
|---|---|
| Target | Hepatitis B surface antigen |
| Tissue Specificity | Reacts with the following HbsAg subtypes : ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-, ayw3 (Fer).† † |
| Application Notes | ELISA: Use at an assay dependent dilution. This antibody is recommended for use in an ELISA pair with GTX22039. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide |
