| Product Name | Her3 / ErbB3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to c - erbB - 3 / HER - 3The gene for c-erbB-3/HER-3 is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6.2kb mRNA which is translated into a 160/180kD glycoprotein. The cerbB-3/HER-3 gene encodes secreted as well as transmembrane receptor tyrosine kinase due to alternative splicing. The c-erbB-3 is overexpressed in a variety of tumors including breast, stomach, pancreas, and colon. |
| Immunogen | A synthetic peptide (aa 71-86) from the ligand binding domain (corresponding to aa AMNEFSTLPLPNLRVV-Cys) of human c-erbB-3/HER-3 oncoprotein |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-PIP |
| For IHC-P: Use at an assay dependent dilution. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues. For IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | c-erbB-3 c-erbB3 p45-sErbB3 p85-sErbB3 ErbB-3 ErbB3 MDABF1 P21860 cErbB3 erbB3-S p180ErbB3 p85sErbB3 erbB3S p45sErbB3 190151 MGC88033 2065 HER3 MDA-BF-1 p180-ErbB3 c ErbB3 ErbB 3 erbB3 S c erbB 3 MDA BF 1 p45 sErbB3 p85 sErbB3 p1 |
|---|---|
| Target | c-ErbB3 |
| Positive Control | Skeletal Muscle |
|---|---|
| Application Notes | For IHC-P: Use at an assay dependent dilution. No special pretreatment is required for immuno-histochemical staining of formalin-fixed tissues. For IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4, containing 0.2% BSA and |
