Application
ELISA analysis of control antigen and antigen using HEXA antibody [3F10].Application
FACS analysis of HeLa cells using HEXA antibody [3F10] (green) or a negative control (red).Application
WB analysis of (1) L1210 and (2) HL7702 lysates using HEXA antibody [3F10].Application
WB analysis of human HEXA (a.a. 29-181) recombinant protein using HEXA antibody [3F10].| Product Name | HEXA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal Antibody [3F10] to HEXAThis gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009] |
| Immunogen | The immunogen corresponding to human HEXA expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 3F10 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | TSD |
|---|---|
| Target | HEXA |
| Molecular Weight(MW) | 60.7 kDa (note) |
Application
ELISA analysis of control antigen and antigen using HEXA antibody [3F10].
Application
FACS analysis of HeLa cells using HEXA antibody [3F10] (green) or a negative control (red).
Application
WB analysis of (1) L1210 and (2) HL7702 lysates using HEXA antibody [3F10].
Application
WB analysis of human HEXA (a.a. 29-181) recombinant protein using HEXA antibody [3F10].| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
