Mouse monoclonal [4F4] to hnRNP C1 + C2The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
Immunogen
RNP?s eluted from oligo (dT) cellulose column
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F4
Host Species
Mouse
Tested Applications
ELISAICC/IFIPWB
ELISA: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects bands of approximately 41 kDa (C1) and 43 kDa (C2). Optimal dilutions/concentrations should be determined by the end user.:
ELISA: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects bands of approximately 41 kDa (C1) and 43 kDa (C2). Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.