| Product Name | Human IgG4 Heavy chain antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [5C7] to Human IgG4 Heavy chainImmunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. |
| Immunogen | IgG4 from human serum. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5C7 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| For indirect ELISA: Use at a dilution of 1:100,000. GTX21930 can be used for coating and as a conjugate. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Target | Human IgG4 Heavy chain |
|---|---|
| Tissue Specificity | Subclass-specific for human IgG4. No allotype restriction. Fc-region specific. |
| Application Notes | For indirect ELISA: Use at a dilution of 1:100,000. GTX21930 can be used for coating and as a conjugate. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide |
