| Product Name | Human Papilloma virus type 16/18 E6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [C1P5] to HPV16 and HPV18 E6The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. C1P5 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. |
| Immunogen | Gel-purified HPV-18 E6-beta galactosidase fusion protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | C1P5 |
| Host Species | Mouse |
| Tested Applications | IHC-PIPWB |
| Recommended Starting Dilutions: For IP: Use at an assay dependant dilution. For IHC-P: Use at an assay dependant dilution. For WB: Use at a dilution of 1:100-1:2000. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | HPV 16 E6 HPV 18 E6 HPV E6 |
|---|---|
| Target | HPV16 + HPV18 E6 |
| Application Notes | Recommended Starting Dilutions: For IP: Use at an assay dependant dilution. For IHC-P: Use at an assay dependant dilution. For WB: Use at a dilution of 1:100-1:2000. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline |
