| Product Name | ICAM3 antibody [MEM-04] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Monoclonal Antibody to ICAM3The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq] |
| Immunogen | Leukocytes of a patient suffering from LGL-type leukemia. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-04 |
| Host Species | Mouse |
| Tested Applications | FACS |
| FuncS: The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1). | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ICAM-R, ICAMR, 146631, CD50, ICAM3, 3385, P32942, CDW50, ICAM R |
|---|---|
| Target | ICAM3 |
| Tissue Specificity | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. |
| Application Notes | FuncS: The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1). |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Azide free phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4 |
