Mouse monoclonal [MEM-171] to ICAM3The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq]
Immunogen
Tissue / cell preparation (Human granulocytes).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MEM-171
Host Species
Mouse
Tested Applications
FACS,IP
FACS: Use at an assay dependant concentration. IP: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Surface staining of JURKAT human leukemia T cell line with anti-human ICAM3: FITC
Application Notes
FACS: Use at an assay dependant concentration. IP: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.