| Product Name | IDO1 antibody [10.1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [10.1] to IDO1This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
| Immunogen | Peptide corresponding to amino acids 78-184 of human IDO fused to GST. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG3 |
| Clone Number | 10.1 |
| Host Species | Mouse |
| Tested Applications | ICC/IF,IHC-F,WB |
| Species Reactivity | Human,Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | INDO , IDO , IDO-1 , indoleamine 2,3-dioxygenase 1 |
|---|---|
| Target | IDO1 |
| Tissue Specificity | This antibody recognizes Indoleamine-pyrrole 2,3 - dioxygenase (IDO). |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.1% Sodium Azide (NaN3). |
