Mouse monoclonal antibody [CH8920] to IFN gammaMammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
Immunogen
Recombinant full length protein.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CH8920
Host Species
Mouse
Tested Applications
ELISA
For ELISA: Use at a concentration of 0.1 ng/ml. Not suitable for IHC-P from normal kidney, liver with cirrhosis, normal lung, or lung cancer samples. Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Gene Synonyms
Macrophage activating factor (MAF), Type II Interferon, Immune interferon, IFN gamma, IFNG, IFN immune, T cell interferon, IFI, Interferon gamma precursor, Interferon gamma, IFG
Target
IFN gamma
Tissue Specificity
This antibody recognised both recombinant and native human IFN gamma.
Cellular Localization
Secreted
Light Chain Type
Kappa
Application Notes
For ELISA: Use at a concentration of 0.1 ng/ml. Not suitable for IHC-P from normal kidney, liver with cirrhosis, normal lung, or lung cancer samples. Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.